Description

Deae-Dextran is a cationic polysaccharide derivative widely used as a versatile tool in biochemistry and molecular biology. Its primary value lies in its ability to bind nucleic acids and proteins, facilitating critical research and industrial processes. This product is essential for professionals in the biopharmaceutical, vaccine development, and life science research sectors. We supply high-purity Deae-Dextran CAS NO 9015-73-0 to support consistent and reliable results in demanding applications.

Application

• Transfection Reagent: Used as a cationic polymer to form complexes with DNA or RNA for introducing nucleic acids into mammalian cells in vitro.
• Vaccine Adjuvant: Employed in immunological research and some vaccine formulations to enhance the immune response to antigens.
• Protein Purification: Acts as a weak anion exchanger in chromatography for the separation and purification of proteins, enzymes, and other biomolecules.
• Cell Membrane Studies: Utilized to precipitate macromolecules and study membrane interactions and permeability.
• Gene Delivery Research: Serves as a non-viral vector in foundational research for gene therapy and genetic engineering.
• Precipitating Agent: Used to precipitate nucleic acids or acidic polysaccharides from solution in various biochemical assays.

Basic Information

Product Name	Deae-Dextran
CAS No.	9015-73-0
Molecular Formula	(C6H10O5)n·(C2H6ClNO)m
Molecular Weight	Variable (40,000 - 500,000 typical)
Synonyms	DEAE-Dextran; Diethylaminoethyl-Dextran; Dextran, 2-(diethylamino)ethyl ether; Dextran DEAE; DEAE-Dextran chloride; Dextran, DEAE-; Poly[oxy-1,2-ethanediyl(dimethyliminio)-1,2-ethanediyl chloride], dextran-based; Cationic Dextran
EINECS	Contact for details

Quality Control

Our Deae-Dextran is manufactured under a rigorous quality management system. Each batch is tested to ensure it meets stringent specifications for identity, purity, substitution degree, and molecular weight distribution. A comprehensive Certificate of Analysis (COA) documenting these results is provided with every shipment. We support compliance with cGMP and other relevant regulatory frameworks for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or granules
Identification (IR)	Conforms to structure
Assay (Nitrogen Content)	3.0 - 4.0 % (or as per grade)
Substitution Degree (DEAE groups)	0.3 - 0.6 per glucose unit (typical)
Molecular Weight	Specified range (e.g., 40kDa, 500kDa)
Loss on Drying	< 10.0 %
Residue on Ignition (Sulfated Ash)	< 1.0 %
Heavy Metals	< 20 ppm
Microbial Limits	< 1000 CFU/g (or as per grade)
Endotoxin (for specific grades)	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.