Description

Hexadecylphospho(N,N,n-Trimethylamino)Hexanol is a specialized cationic phospholipid derivative, also known as a phosphocholine analog. This compound is valued for its unique amphiphilic structure, which imparts excellent membrane-targeting and self-assembly properties. It is primarily utilized in advanced pharmaceutical research, particularly in the development of novel drug delivery systems such as liposomes and lipid nanoparticles, as well as in biochemical studies of cell membranes.

Application

• Lipid Nanoparticle (LNP) Formulation: A key structural lipid for constructing stable, cationic, or ionizable lipid nanoparticles used in mRNA and siRNA delivery.
• Liposome Production: Serves as a functional component in the creation of cationic liposomes for gene transfection and targeted drug delivery applications.
• Biomimetic Membrane Research: Used to create model membrane systems for studying protein-lipid interactions, membrane fusion, and permeability.
• Cosmetic Actives Carrier: Employed in high-end cosmetic formulations to enhance the skin penetration and stabilization of active ingredients.
• Diagnostic Reagents: Can be incorporated into diagnostic assays and biosensors that rely on membrane-bound recognition events.
• Surface Modification: Used to coat surfaces or materials to impart biocompatible or specific interactive properties.

Basic Information

Product Name	Hexadecylphospho(N,N,n-Trimethylamino)Hexanol
CAS No.	133261-51-5
Molecular Formula	C26H57NO4P
Molecular Weight	478.71 g/mol
Synonyms	1-Hexadecylphospho-2-(N,N,N-trimethylammonio)hexanol; C16 Phosphocholine Analog; Hexadecylphosphocholine Hexanol Ester; 1-O-Hexadecyl-2-O-(6-trimethylammonio)hexyl-sn-glycero-3-phosphocholine; Phospholipid 133261-51-5; Cationic Lipid for LNP; PC-Lipid Derivative; HDP-TMAH
EINECS	Contact for details

Quality Control

Every batch of Hexadecylphospho(N,N,n-Trimethylamino)Hexanol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.