Description

Starburst(R) (Pamam) Dendrimer, Generation 2.5 is a precisely engineered, hyperbranched polymer with a well-defined, three-dimensional architecture and a high density of surface functional groups. This unique structure makes it an invaluable nanoscale scaffold and delivery platform for advanced materials science and biomedical research. It is essential for researchers and formulators in drug delivery, gene therapy, diagnostic imaging, and nanotechnology who require a monodisperse, customizable polymeric building block.

Application

• Drug Delivery Systems: As a nanocarrier for targeted and controlled release of therapeutic agents, enhancing solubility and bioavailability.
• Gene Transfection: Complexation with DNA or RNA for non-viral gene delivery and gene therapy applications.
• Diagnostic Imaging: Serving as a platform for attaching contrast agents (e.g., for MRI) or fluorescent probes.
• Catalyst Support: Immobilization of metal nanoparticles or catalytic sites within its dendritic structure for high-efficiency catalysis.
• Surface Modification: Functionalization of materials (e.g., sensors, chips) to create tailored surface properties and biointerfaces.
• Nanocomposite Materials: Acting as a crosslinker or additive to modify the mechanical and thermal properties of polymers.
• Scaffold for Dendritic Polymers: Used as a core for synthesizing higher-generation dendrimers or more complex dendritic architectures.

Basic Information

Product Name	Starburst(R) (Pamam) Dendrimer, Generation 2.5
CAS No.	156260-01-4
Molecular Formula	C62H128N26O12
Molecular Weight	Approx. 1268.8 g/mol
Synonyms	PAMAM Dendrimer, Generation 2.5, Ethylenediamine Core; Poly(amidoamine) Dendrimer, G2.5; Starburst Dendrimer, PAMAM, half-generation 2.5; Dendritic Poly(amidoamine), NH2 terminated, G=2.5; PAMAM-NH2 G2.5; Nano-structured Polymer G2.5; Polypropylenimine Tetraamine Dendrimer (related class); Astramol™ (alternative trade name for similar PAMAM dendrimers)
EINECS	Contact for details

Quality Control

Our Starburst(R) PAMAM Dendrimers are produced under stringent conditions to ensure batch-to-batch consistency and high purity, critical for sensitive research and development applications. Each batch is characterized using advanced analytical techniques including size-exclusion chromatography (SEC/GPC), NMR spectroscopy, and mass spectrometry to confirm molecular weight, polydispersity, and functional group integrity. Certificates of Analysis (COA) detailing these specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). For long-term stability, consider storage under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C. The product is moisture-sensitive; ensure the container is sealed after each use to prevent absorption of water vapor.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (SEC/GPC)	> 95% (Dendrimer content)
Polydispersity Index (PDI)	< 1.05
Molecular Weight	~1268 g/mol (Theoretical)
Functional Groups (Titration)	16 Primary Amine groups (-NH2) per molecule
Solubility	Water, Methanol, DMSO
Residual Solvent (GC)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.