Description

Paf (C18) is a synthetic platelet-activating factor (PAF) analog, specifically the C18 homolog, widely used in biochemical and pharmacological research. This compound is crucial for studying cellular signaling pathways, inflammation, and immune responses due to its potent biological activity. It serves as an essential research tool for scientists in pharmaceutical development, academic institutions, and biotechnology companies investigating receptor mechanisms and therapeutic targets.

Application

• Biochemical Research: Used as a standard and agonist in studies of PAF receptor (PAFR) signaling and function.
• Pharmacological Studies: Employed to investigate inflammatory pathways, bronchoconstriction, and anaphylaxis in preclinical models.
• Cell Signaling Analysis: A key tool for activating phospholipase A2 and modulating intracellular calcium mobilization in various cell types.
• Drug Discovery: Serves as a reference compound for screening and developing PAF receptor antagonists and anti-inflammatory agents.
• Academic & Institutional Research: Fundamental for basic science research in immunology, cardiology, and neurology departments.

Basic Information

Product Name	Paf (C18)
CAS No.	74389-69-8
Molecular Formula	C26H54NO7P
Molecular Weight	523.68 g/mol
Synonyms	PAF C-18; 1-O-Octadecyl-2-acetyl-sn-glycero-3-phosphocholine; Octadecyl PAF; C18-PAF; AGEPC (C18:0); Platelet Activating Factor (C18); PAF (1-O-Octadecyl); Lyso-PAF C18:0 Acetate
EINECS	Contact for details

Quality Control

Our Paf (C18) is produced under strict quality management systems to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals to guarantee reliable and reproducible experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, ethanol; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.