Description

Brefeldin C is a macrocyclic lactone metabolite produced by certain fungal species, recognized for its potent biological activity. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a protein transport inhibitor, disrupting vesicle trafficking within the Golgi apparatus. It serves as a critical research tool for scientists and developers in the fields of cell biology, pharmacology, and antifungal agent discovery.

Application

• Biochemical Research: Used as a specific inhibitor of protein transport and secretion in eukaryotic cells to study intracellular trafficking mechanisms.
• Pharmaceutical R&D: Investigated as a lead compound or reference standard in the development of novel antifungal and anticancer agents.
• Cell Biology Studies: Employed to induce the rapid redistribution of Golgi proteins into the endoplasmic reticulum (ER), facilitating studies on organelle structure and function.
• Mechanism of Action Studies: Serves as a probe to elucidate the pathways of vesicle formation and the action of other bioactive compounds.
• Natural Product Chemistry: Acts as a reference standard for the identification and quantification of Brefeldin analogs in microbial extracts or fermentation broths.

Basic Information

Product Name	Brefeldin C
CAS No.	73899-78-2
Molecular Formula	C16H24O4
Molecular Weight	280.36 g/mol
Synonyms	BFA C; Cyanein; Decumbin; 4,6,8,10,16-Pentahydroxy-7,18-dimethyl-14-propyl-3,20,22-trioxatricyclo[18.3.0.02,6]tricosa-4,8,10,16-tetraen-9-one; Ascotoxin; Antibiotic 1830; Antibiotic 1833
EINECS	Contact for details

Quality Control

Our Brefeldin C is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade biochemicals to guarantee reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 2.0% (KF)
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.