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1-Oleoyl-Sn-Glycero-3-Phosphate Sodium Salt CAS NO 72777-87-8


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CAS No.:72777-87-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Oleoyl-Sn-Glycero-3-Phosphate Sodium Salt is a high-purity, synthetic phospholipid derivative, specifically a lysophosphatidic acid (LPA) analogue. This compound is a critical biochemical reagent and a key intermediate in lipid research and pharmaceutical development. It is essential for researchers and manufacturers in the life sciences, particularly those focused on lipid signaling, membrane biophysics, and drug delivery systems.

Application

  • Biochemical Research: A vital standard and substrate for studying lysophosphatidic acid (LPA) receptor signaling pathways, lipid metabolism, and enzyme kinetics (e.g., phospholipases).
  • Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel lipid-based therapeutics and prodrugs.
  • Liposome & Drug Delivery: Used as a component in the formulation of liposomes and lipid nanoparticles (LNPs) to enhance membrane fusion properties and improve drug encapsulation efficiency.
  • Cell Culture & Diagnostics: Employed in specialized cell culture media as a lipid supplement and in the development of diagnostic assays targeting lipid biomarkers.
  • Reference Standard: Acts as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical and academic laboratories.

Basic Information

Product Name 1-Oleoyl-Sn-Glycero-3-Phosphate Sodium Salt
CAS No. 72777-87-8
Molecular Formula C21H40NaO7P
Molecular Weight 458.50 g/mol
Synonyms 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt); LPA (18:1) sodium salt; Lysophosphatidic Acid (18:1) sodium salt; (9Z)-Octadec-9-enoic acid, 1-(hydroxymethyl)-2-(phosphonooxy)ethyl ester, sodium salt; 1-Oleoyl LPA sodium salt; Oleoyl lysophosphatidic acid sodium salt; sn-Glycerol 3-phosphate 1-oleoyl sodium salt
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Quality Control

Our 1-Oleoyl-Sn-Glycero-3-Phosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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