Description

Trimethyl-[2-[[2-Octadecanoyloxy-3-[(Z)-Octadec-9-Enoyl]oxy-Propoxy]-Oxido-Phosphoryl]oxyethyl]azanium is a high-purity synthetic phospholipid derivative, specifically a cationic lipid, engineered for advanced formulation and delivery applications. Its molecular structure is critical for creating stable, positively charged complexes that enhance cellular uptake and encapsulation efficiency. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality lipid components for next-generation products.

Application

• Lipid Nanoparticle (LNP) Formulation: A key cationic lipid component for the encapsulation and delivery of nucleic acids (mRNA, siRNA, DNA) in therapeutic and vaccine development.
• Non-Viral Gene Delivery Systems: Used to construct lipoplexes and other transfection reagents for efficient gene transfer in vitro and in vivo research.
• Advanced Drug Delivery: Facilitates the targeted delivery of hydrophobic and hydrophilic active pharmaceutical ingredients (APIs) by forming stable liposomal and micellar structures.
• Biomimetic Membrane Research: Serves as a synthetic analog for studying membrane biophysics, protein-lipid interactions, and cellular signaling processes.
• Cosmetic & Dermal Formulations: Incorporated into nanocarrier systems for the enhanced penetration and stability of active ingredients in skincare products.
• Diagnostic Agent Carrier: Utilized to encapsulate imaging contrast agents or dyes for improved biodistribution and targeting in diagnostic applications.

Basic Information

Product Name	Trimethyl-[2-[[2-Octadecanoyloxy-3-[(Z)-Octadec-9-Enoyl]oxy-Propoxy]-Oxido-Phosphoryl]oxyethyl]azanium
CAS No.	7319-55-3
Molecular Formula	C₄₇H₉₄NO₈P
Molecular Weight	832.23 g/mol
Synonyms	1,2-Distearoyl-3-trimethylammonium-propane (chloride salt); DSTAP; 1,2-Dioleoyl-3-trimethylammonium-propane (analog); TAP Lipid; Cationic lipid 7319-55-3; 3-[(Z)-Octadec-9-enoyl]-2-octadecanoyloxypropyl (2-trimethylammonioethyl) phosphate; N,N,N-Trimethyl-2-[[(1-oxooctadecyl)oxy][(1-oxo-9-octadecenyl)oxy]phosphinyl]oxy]-Ethanaminium
EINECS	Contact for details

Quality Control

Our Trimethyl-[2-[[2-Octadecanoyloxy-3-[(Z)-Octadec-9-Enoyl]oxy-Propoxy]-Oxido-Phosphoryl]oxyethyl]azanium is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and biotech applications. Certificates of Analysis (COA) with full traceability are provided, and we support compliance with cGMP, ICH Q7 guidelines, and REACH regulations for global supply.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C ± 5°C under an inert atmosphere (e.g., nitrogen or argon). The product is moisture-sensitive; ensure the container is kept in a dry environment and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.