Description

1,2-Dilauroyl-Sn-Glycero-3-Phosphoethanolamine is a synthetic, saturated phospholipid belonging to the phosphatidylethanolamine (PE) class, specifically featuring lauric acid (C12:0) chains. This compound is a critical building block in the formulation of advanced lipid-based delivery systems, offering superior stability and biocompatibility. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries developing liposomes, lipid nanoparticles (LNPs), and other biomimetic membranes for drug delivery, diagnostics, and cosmetic applications.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, uniform vesicles for mRNA, siRNA, and small molecule drug delivery.
• Biomimetic Membrane Research: Used to construct model cell membranes for studying membrane protein interactions, permeability, and fusion processes.
• Cosmetic & Dermal Delivery Systems: Incorporated into nanocarriers to enhance the skin penetration and stability of active ingredients in topical products.
• Diagnostic Reagent Preparation: Serves as a component in diagnostic kits and assays that utilize liposomal encapsulation for signal amplification.
• Cryopreservation Media: Used as a protective agent in formulations designed to preserve cells and tissues during freezing.
• Biophysical Studies: Employed in research involving membrane fluidity, phase transition behavior, and lipid bilayer dynamics due to its defined saturated chains.

Basic Information

Product Name	1,2-Dilauroyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	59752-57-7
Molecular Formula	C29H58NO8P
Molecular Weight	579.75 g/mol
Synonyms	DLPE; 1,2-Dilauroylphosphatidylethanolamine; Dilauryphosphatidylethanolamine; Phosphatidylethanolamine, 1,2-didodecanoyl-; PE(12:0/12:0); 1,2-Didodecanoyl-sn-glycero-3-phosphoethanolamine; L-α-Phosphatidylethanolamine, dilauroyl; (2R)-2,3-Bis(dodecanoyloxy)propyl (2-aminoethyl) phosphate
EINECS	Contact for details

Quality Control

Our 1,2-Dilauroyl-Sn-Glycero-3-Phosphoethanolamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Solubility	Soluble in chloroform, methanol, ethanol; insoluble in water
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.