Description

N(1),O(2)-Dioctanoyl Cyclic Amp CAS NO 57329-09-6 is a chemically modified, lipophilic derivative of cyclic adenosine monophosphate (cAMP), designed for enhanced membrane permeability and stability in biological research. This compound is critical for researchers investigating intracellular signaling pathways, particularly those involving protein kinase A (PKA) activation, with greater efficiency than standard cAMP. It is primarily utilized in advanced biochemical and pharmacological studies within academic research institutions, pharmaceutical R&D laboratories, and biotechnology companies focused on signal transduction and drug discovery.

Application

• Biochemical Research: As a potent, cell-permeable activator of Protein Kinase A (PKA) for studying intracellular cAMP-mediated signaling cascades.
• Pharmaceutical Development: Used as a reference standard or tool compound in high-throughput screening assays to identify novel therapeutics targeting G-protein-coupled receptors (GPCRs).
• Cell Biology Studies: Investigation of cellular processes such as gene expression, metabolism, ion channel function, and cell differentiation influenced by cAMP pathways.
• Neuroscience Research: Exploration of synaptic plasticity, neurotransmitter release, and neuronal excitability modulated by PKA.
• Metabolic Disorder Research: Probing the role of cAMP in insulin secretion, gluconeogenesis, and lipid metabolism for potential diabetes and obesity research.
• Cardiovascular Research: Studying the effects on cardiac muscle contractility and vascular tone regulation.

Basic Information

Product Name	N(1),O(2)-Dioctanoyl Cyclic Amp
CAS No.	57329-09-6
Molecular Formula	C26H43N5O8P
Molecular Weight	584.62 g/mol
Synonyms	N6,O2'-Dioctanoyl-cAMP; 8-(Octanoyloxymethyl)-N6-octanoyladenosine-3',5'-cyclic monophosphate; Dioctanoyl cAMP; N6,O2'-Dioctanoyladenosine 3',5'-cyclic monophosphate; Lipophilic cAMP derivative; Cell-permeable cAMP analog; Dibutyryl cAMP analog (higher chain); cAMP, N6,O2'-dioctanoyl-
EINECS	Contact for details

Quality Control

Our N(1),O(2)-Dioctanoyl Cyclic Amp is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) for identity confirmation, and NMR spectroscopy. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.