Description

Benzilylcholine Mustard is a potent and selective alkylating agent derived from choline, primarily used as an irreversible muscarinic acetylcholine receptor antagonist in pharmacological research. This compound is critical for studying receptor structure, function, and signal transduction pathways in the nervous system. It is an essential tool for neuroscientists, pharmacologists, and medicinal chemists engaged in receptor characterization and the development of targeted therapeutic agents.

Application

• Pharmacological Research: Irreversible blockade of muscarinic acetylcholine receptors (mAChRs) for receptor mapping and characterization studies.
• Neurochemistry: Investigation of cholinergic signaling pathways and the physiological roles of specific mAChR subtypes in the central and peripheral nervous systems.
• Medicinal Chemistry & Drug Discovery: A key tool compound for validating drug targets and developing new therapeutic agents for neurological disorders.
• Biochemical Assay Development: Used in the development of in vitro and ex vivo binding assays to study receptor-ligand interactions.
• Academic & Institutional Research: Fundamental research in universities and institutes focusing on neuropharmacology and cellular communication.

Basic Information

Product Name	Benzilylcholine Mustard
CAS No.	5746-42-9
Molecular Formula	C20H25ClN2O2
Molecular Weight	360.88 g/mol
Synonyms	BCM; Benzilylcholine Mustard Hydrochloride; 2-[(2-Chloroethyl)methylamino]ethyl Benzilate; Mustard Benziloylcholine; NSC 154849; (2-((2-Chloroethyl)(methyl)amino)ethyl) 2-hydroxy-2,2-diphenylacetate; Muscarinic Receptor Alkylating Agent
EINECS	Contact for details

Quality Control

Our Benzilylcholine Mustard is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals to guarantee reliable and reproducible experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in water, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.