Description

N1-[2-((1S)-1-[(3-Aminopropyl)Amino]-4-[Di(3-Amino-Propyl)Amino]Butylcarboxamido)Ethyl]-3,4-Di[Oleyloxy]-Benzamide is a sophisticated, multi-functional cationic lipid derivative designed for advanced formulation applications. This compound is engineered to act as a highly effective transfection reagent and delivery vector, crucial for modern biopharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and gene therapy sectors for the encapsulation and delivery of nucleic acids.

Application

• Lipid Nanoparticle (LNP) Formulation: A key structural component for constructing stable, non-viral delivery systems for mRNA, siRNA, and other genetic materials.
• Gene Transfection & Delivery: Facilitates the efficient introduction of DNA, RNA, or CRISPR-Cas9 components into a wide range of cell types in vitro and in vivo.
• Vaccine Development: Used in the formulation of next-generation mRNA-based vaccines and therapeutic modalities.
• Drug Delivery Systems: Serves as a cationic carrier for the targeted delivery of small molecule drugs, proteins, and oligonucleotides.
• Bioconjugation & Linker Chemistry: The multiple amine groups provide sites for conjugation with targeting ligands, fluorescent dyes, or other functional molecules.
• Research & Development: A critical reagent for academic and industrial R&D focused on novel non-viral gene delivery mechanisms and nanomedicine.

Basic Information

Product Name	N1-[2-((1S)-1-[(3-Aminopropyl)Amino]-4-[Di(3-Amino-Propyl)Amino]Butylcarboxamido)Ethyl]-3,4-Di[Oleyloxy]-Benzamide
CAS No.	464926-03-2
Molecular Formula	C62H119N7O4
Molecular Weight	1026.66 g/mol
Synonyms	Multi-Amino Cationic Lipid; Cationic Transfection Lipid; (S)-DOBAT; 1,2-Dioleyloxy-3-(N,N-dimethylamino)propane analog; Polyamine-based cationic lipid; Branched-chain amino lipid; Gene delivery lipid; Lipidoid; Lipofectamine analog; Oleyl-based transfection reagent
EINECS	Contact for details

Quality Control

Our N1-[2-((1S)-1-[(3-Aminopropyl)Amino]-4-[Di(3-Amino-Propyl)Amino]Butylcarboxamido)Ethyl]-3,4-Di[Oleyloxy]-Benzamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and performance for critical research and formulation work. Certificates of Analysis (COA) detailing purity, identity, and related substance profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.