Description

8-(4-Chlorophenylthio)-Camp Sodium Salt Membrane-Permeable An is a chemically modified, cell-permeable derivative of cyclic adenosine monophosphate (cAMP), designed for advanced biochemical and pharmacological research. This compound is a crucial tool for modulating intracellular cAMP signaling pathways in live cells and tissues without the need for microinjection or electroporation. It is primarily utilized by researchers and scientists in the fields of cell biology, neuroscience, and drug discovery to study G-protein coupled receptor (GPCR) function, ion channel regulation, and cellular metabolism.

Application

• Intracellular Signal Transduction Research: Used as a membrane-permeable cAMP analog to activate protein kinase A (PKA) and other cAMP-dependent pathways within live cells.
• Neuroscience Studies: Investigates the role of cAMP in neuronal plasticity, long-term potentiation (LTP), and neurotransmitter release.
• Cardiovascular Research: Explores cAMP-mediated effects on heart muscle contractility and vascular smooth muscle relaxation.
• Drug Discovery Screening: Serves as a reference compound or positive control in high-throughput screening assays targeting GPCRs and phosphodiesterases (PDEs).
• Metabolic Disorder Research: Studies the modulation of insulin secretion, gluconeogenesis, and lipolysis in metabolic tissues.
• Cell Culture & In Vitro Models: Applied in primary cell cultures and organoid models to manipulate cellular differentiation and function.

Basic Information

Product Name	8-(4-Chlorophenylthio)-Camp Sodium Salt Membrane-Permeable An
CAS No.	41941-66-6
Molecular Formula	C16H15ClN5NaO6PS
Molecular Weight	502.80 g/mol
Synonyms	8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate sodium salt; 8-CPT-cAMP sodium salt; 8-(4-Chlorophenylthio)-cAMP sodium salt; 8-CPT-cyclic AMP sodium salt; Membrane-Permeable cAMP Analog; 8-(p-Chlorophenylthio)-cAMP Na salt; 8-CPT-cAMP
EINECS	Contact for details

Quality Control

Our 8-(4-Chlorophenylthio)-Camp Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.