Description

Alda 1 is a potent and selective small-molecule activator of the enzyme aldehyde dehydrogenase 2 (ALDH2). This compound is of significant interest in biochemical and pharmaceutical research for its role in modulating cellular metabolism and protecting against oxidative stress. It is primarily utilized by researchers and developers in the fields of pharmacology, toxicology, and metabolic disease studies to investigate pathways related to alcohol metabolism, cardiovascular health, and ischemic injury.

Application

• Biochemical Research: A key tool for studying the function and modulation of the ALDH2 enzyme in vitro and in vivo.
• Pharmacology Development: Used in preclinical studies to explore therapeutic potential for conditions like heart failure, myocardial infarction, and alcoholic liver disease.
• Toxicology Studies: Employed to investigate cellular protection mechanisms against acetaldehyde and other reactive aldehyde-induced toxicity.
• Metabolic Disorder Research: Applied in models of metabolic syndrome and diabetes to understand the role of ALDH2 in glucose and lipid metabolism.
• Neuroscience Research: Utilized to examine neuroprotective effects in models of stroke and neurodegenerative diseases.
• High-Throughput Screening (HTS): Serves as a reference compound in assay development for identifying novel ALDH2 modulators.

Basic Information

Product Name	Alda 1
CAS No.	349438-38-6
Molecular Formula	C14H12N2O3S
Molecular Weight	288.32 g/mol
Synonyms	N-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide; Alda-1; ALDH2 Activator; 5-[(2,6-Dichlorobenzoyl)amino]methyl]-1,3-benzodioxole; 349438-38-6; Benzamide, N-[(1,3-benzodioxol-5-yl)methyl]-2,6-dichloro-
EINECS	Contact for details

Quality Control

Our Alda 1 is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA), documenting identity, purity, and assay results, is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.