Description

N(6)-2'-o-Dibutyryl-8-Thiocyclic Amp is a chemically modified derivative of adenosine monophosphate, designed for enhanced stability and membrane permeability in biological research. This compound matters as a potent cell-permeable activator of cyclic AMP-dependent pathways, offering researchers a valuable tool for modulating intracellular signaling. It is primarily needed by pharmaceutical R&D teams, biochemical researchers, and academic institutions focused on signal transduction, metabolic studies, and drug discovery.

Application

• Biochemical Research: Used as a cell-permeable activator of protein kinase A (PKA) and other cAMP-dependent signaling pathways.
• Pharmaceutical Development: Serves as a reference standard and a key intermediate in the synthesis of novel therapeutic agents targeting metabolic disorders.
• Cell Biology Studies: Employed to investigate the role of cAMP in cellular processes such as gene expression, ion channel function, and metabolism.
• Enzyme Assays: Acts as a substrate or modulator in enzymatic studies related to adenylate cyclase and phosphodiesterase activity.
• Metabolic Research: Utilized in studies exploring energy metabolism, lipolysis, and gluconeogenesis regulation.
• Signal Transduction Pathways: A critical tool for probing and manipulating intracellular second messenger systems in vitro and in cell culture models.

Basic Information

Product Name	N(6)-2'-o-Dibutyryl-8-Thiocyclic Amp
CAS No.	34409-10-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphorothioate; 8-Thio-cAMP, dibutyryl; Dibutyryl 8-thiocyclic AMP; 8-Thio-dibutyryl-cAMP; N6,2'-O-Dibutyryl-8-thioadenosine-3',5'-cyclic monophosphate; 8-Thio-cyclic AMP dibutyrate; DB-8-Thio-cAMP
EINECS	Contact for details

Quality Control

Our N(6)-2'-o-Dibutyryl-8-Thiocyclic Amp is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, Ethanol; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.