Description

Serca2A Activator A is a specialized small molecule compound designed to modulate the activity of the SERCA2a calcium pump, a key regulator of cardiac muscle contractility. This compound is of significant interest in cardiovascular research for its potential to enhance cardiac function. It serves as a critical research tool for pharmaceutical R&D and academic laboratories focused on heart failure, calcium signaling pathways, and novel therapeutic discovery. The product is supplied under the CAS registry number 2139330-34-8.

Application

• Cardiovascular Research: Primary tool for investigating SERCA2a function and calcium handling in cardiac myocytes.
• Drug Discovery & Development: Used as a reference compound or positive control in high-throughput screening (HTS) campaigns for heart failure therapeutics.
• Mechanistic Studies: Enables detailed study of calcium ATPase pump kinetics and regulation in both healthy and diseased tissue models.
• Preclinical In Vitro/Ex Vivo Models: Applied in isolated heart (Langendorff) preparations and cellular assays to assess contractility improvements.
• Signal Transduction Pathways: Useful for probing the broader network of calcium-dependent signaling cascades in muscle biology.
• Biochemical Assay Development: Serves as a key component in developing and validating assays for SERCA2a activity.

Basic Information

Product Name	Serca2A Activator A
CAS No.	2139330-34-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SERCA2a Activator A; Cardiac SERCA Activator; SERCA2a Pump Modulator; Calcium ATPase Activator; 2139330-34-8; (Compound name based on IUPAC nomenclature - contact for details); Research Compound for Heart Failure
EINECS	Contact for details

Quality Control

Our Serca2A Activator A is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation. A detailed Certificate of Analysis (COA) containing purity, identity, and related substance data is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at -20°C under inert atmosphere. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.