Description

Benzoyl Fluoride, 3-Cyano-2,4,5-Trifluoro- (9Ci) is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl and cyano substituents, which are critical for modulating the electronic properties and metabolic stability of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores to enhance bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to the desired dielectric and luminescent properties.
• Polymer Modification: Employed to introduce fluorine-containing functional groups into polymer backbones, enhancing material properties like chemical resistance and thermal stability.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex biaryl systems.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluorination and the synthesis of complex fluoroorganic molecules.

Basic Information

Product Name	Benzoyl Fluoride, 3-Cyano-2,4,5-Trifluoro- (9Ci)
CAS No.	214774-56-8
Molecular Formula	C8HF4NO
Molecular Weight	203.09 g/mol
Synonyms	3-Cyano-2,4,5-trifluorobenzoyl fluoride; 2,4,5-Trifluoro-3-cyanobenzoyl fluoride; Benzoyl fluoride, 3-cyano-2,4,5-trifluoro-; 3-Cyanobenzoyl fluoride, 2,4,5-trifluoro- derivative; (2,4,5-Trifluoro-3-cyanophenyl)(fluoro)methanone
EINECS	Contact for details

Quality Control

Our Benzoyl Fluoride, 3-Cyano-2,4,5-Trifluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.