Description

5-Chloro-2,4,6-Trifluoroisophthalonitrile is a high-value, multi-functional aromatic intermediate characterized by its unique combination of chloro, fluoro, and nitrile substituents. This compound matters as a critical building block for synthesizing advanced materials and active pharmaceutical ingredients, offering significant reactivity for further functionalization. It is primarily needed by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty polymer industries seeking to develop novel compounds with enhanced properties.

Application

• Agrochemical Intermediate: Serves as a key precursor for the synthesis of modern herbicides and fungicides, leveraging the fluorine atoms to improve biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry to construct complex heterocyclic scaffolds, particularly for candidates targeting central nervous system (CNS) and anti-infective therapies.
• Liquid Crystal & OLED Material Synthesis: Acts as a core unit for creating advanced electronic materials, where the fluorine and nitrile groups contribute to desired dielectric and luminescent properties.
• Polymer Modification: Employed to introduce functional side chains into high-performance polymers, enhancing thermal stability and chemical resistance.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and cyanation processes due to the reactivity of its halogen and nitrile functional groups.
• Research & Development: A valuable compound for academic and industrial R&D focused on fluorine chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	5-Chloro-2,4,6-Trifluoroisophthalonitrile
CAS No.	1897-50-3
Molecular Formula	C8ClF3N2
Molecular Weight	228.56 g/mol
Synonyms	2,4,6-Trifluoro-5-chloroisophthalonitrile; 5-Chloro-2,4,6-trifluorobenzene-1,3-dicarbonitrile; Isophthalonitrile, 5-chloro-2,4,6-trifluoro-; 1,3-Dicyano-2,4,6-trifluoro-5-chlorobenzene; 1897-50-3; 5-Chloro-2,4,6-trifluorobenzene-1,3-dinitrile
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4,6-Trifluoroisophthalonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.