Description

Tetrafluoroterephthalonitrile is a high-value fluorinated aromatic building block with the CAS number 1835-49-0. This compound is critical for the synthesis of advanced materials and specialty chemicals due to its unique combination of a rigid aromatic core, electron-withdrawing nitrile groups, and fluorine substituents. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced polymer industries for creating novel compounds with enhanced properties such as thermal stability, chemical resistance, and specific electronic characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms and nitrile groups contribute to efficacy and environmental persistence profiles.
• Advanced Polymer Monomer: A crucial building block for high-performance polymers, including polyimides, polyamides, and liquid crystal polymers (LCPs), imparting exceptional thermal, chemical, and dielectric properties.
• Organic Electronic Materials: Employed in the research and production of organic semiconductors, electron-transport materials, and non-linear optical (NLO) materials for OLEDs and photovoltaic devices.
• Ligand and Catalyst Development: Functions as a starting material for synthesizing specialized ligands used in catalysis, particularly in cross-coupling and fluorination reactions.
• Fluorinated Dye and Pigment Intermediate: Used to create novel fluorinated dyes and pigments with improved lightfastness and color properties for specialty applications.

Basic Information

Product Name	Tetrafluoroterephthalonitrile
CAS No.	1835-49-0
Molecular Formula	C8F4N2
Molecular Weight	200.09 g/mol
Synonyms	2,3,5,6-Tetrafluoroterephthalonitrile; 1,4-Dicyano-2,3,5,6-tetrafluorobenzene; Terephthalonitrile, tetrafluoro-; Perfluoroterephthalonitrile; Tetrafluorobenzene-1,4-dicarbonitrile; 2,3,5,6-Tetrafluoro-1,4-benzenedicarbonitrile; 2,3,5,6-Tetrafluorobenzene-1,4-dicarbonitrile
EINECS	217-408-9

Quality Control

Our Tetrafluoroterephthalonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO 9001 standards for reliable integration into regulated R&D and production workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	215 - 220 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.