Description

3-Chloro-2,5,6-Trifluoro-1,4-Benzenedicarbonitrile is a high-purity, multi-functional aromatic intermediate featuring a unique combination of halogen substituents. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients, where its specific substitution pattern enables precise molecular design. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorinated and chlorinated motifs into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the chloro- and fluoro-substituents contribute to biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and device efficiency.
• Polymer Modification: Incorporated into specialty polymers and high-performance resins to impart specific chemical resistance, thermal stability, or unique surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a scaffold for constructing complex, multi-halogenated aromatic systems in academic and industrial research.

Basic Information

Product Name	3-Chloro-2,5,6-Trifluoro-1,4-Benzenedicarbonitrile
CAS No.	1929-68-6
Molecular Formula	C8ClF3N2
Molecular Weight	228.55 g/mol
Synonyms	1,4-Dicyano-3-chloro-2,5,6-trifluorobenzene; 3-Chloro-2,5,6-trifluorobenzene-1,4-dicarbonitrile; 2,5,6-Trifluoro-3-chlorobenzene-1,4-dicarbonitrile; 3-Chloro-2,5,6-trifluoroterephthalonitrile; Terephthalonitrile, 3-chloro-2,5,6-trifluoro-; CTFB; 1929-68-6; 3-Chloro-2,5,6-trifluorobenzenedicarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-2,5,6-Trifluoro-1,4-Benzenedicarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.