Description

2-Fluoroterephthalonitrile is a high-value fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique structure, featuring both a fluorine substituent and two cyano groups on a benzene ring, makes it a critical precursor for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging the fluorine atom for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorinated aromatic core enhances biological activity and environmental persistence.
• Functional Material Precursor: Serves as a monomer or cross-linking agent in the production of high-performance polymers, resins, and advanced materials with specific thermal or chemical resistance.
• Liquid Crystal & OLED Material: A valuable starting material for synthesizing fluorinated components used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) to modify electronic properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyano group transformations to construct complex heterocyclic and aromatic systems.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling the exploration of new chemical spaces and property optimization.

Basic Information

Product Name	2-Fluoroterephthalonitrile
CAS No.	1897-53-6
Molecular Formula	C8H3FN2
Molecular Weight	146.12 g/mol
Synonyms	1,4-Dicyano-2-fluorobenzene; 2-Fluoro-1,4-benzenedicarbonitrile; 2-Fluorobenzene-1,4-dicarbonitrile; Terephthalonitrile, 2-fluoro-; 2-Fluoroterephthalodinitrile; 2-FTBN; 2-Fluorodicyanobenzene; 2-Fluoro-1,4-dicyanobenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoroterephthalonitrile is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity assessment, GC for residual solvent analysis, and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.