Description

4-Fluorobenzonitrile is a versatile fluorinated aromatic nitrile building block essential for advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a cyano group on a benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This high-purity compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated active pharmaceutical ingredients (APIs), including kinase inhibitors and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport materials in organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions to introduce the 4-fluorobenzonitrile moiety.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing fluorinated dyes and pigments with enhanced color fastness and performance.

Basic Information

Product Name	4-Fluorobenzonitrile
CAS No.	1194-02-1
Molecular Formula	C7H4FN
Molecular Weight	121.11 g/mol
Synonyms	p-Fluorobenzonitrile; 4-Fluorobenzene carbonitrile; 4-Cyanofluorobenzene; 1-Fluoro-4-cyanobenzene; p-Cyanofluorobenzene; 4-Fluorophenyl cyanide; para-Fluorobenzonitrile; Benzonitrile, 4-fluoro-
EINECS	214-791-4

Quality Control

Our 4-Fluorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline mass
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥98.0% (Standard Grade)
Purity (GC Area %)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.