Description

3-(4-Fluorophenyl)Benzonitrile is a versatile fluorinated aromatic nitrile compound, serving as a critical building block in advanced organic synthesis. Its value lies in the combination of the electron-withdrawing nitrile group and the fluorinated phenyl ring, which are essential for modulating the electronic and steric properties of target molecules. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a core structure for creating fluorinated components in electronic display and lighting materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and asymmetric synthesis.
• Polymer Modification: Acts as a monomer or modifier to introduce fluorine and nitrile functionalities into high-performance polymers.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new fluorinated aromatic systems.

Basic Information

Product Name	3-(4-Fluorophenyl)Benzonitrile
CAS No.	10540-33-7
Molecular Formula	C₁₃H₈FN
Molecular Weight	197.21 g/mol
Synonyms	3-(4-Fluorophenyl)benzonitrile; [1,1'-Biphenyl]-3-carbonitrile, 4'-fluoro-; 4'-Fluoro[1,1'-biphenyl]-3-carbonitrile; 3-(p-Fluorophenyl)benzonitrile; 3-(4-Fluorophenyl)phenyl cyanide; 4-Fluorophenyl-3-cyanobenzene; 3-Cyano-4'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.