Description

4-Chloro-3-(Trifluoromethyl)Benzonitrile is a versatile and high-value aromatic nitrile building block characterized by its trifluoromethyl and chloro substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a common pharmacophore.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions and as a ligand precursor in organometallic chemistry and catalysis research.
• Polymer Modification: Employed to introduce functional groups into polymer chains, modifying properties like chemical resistance and thermal stability for high-performance materials.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Benzonitrile
CAS No.	1735-54-2
Molecular Formula	C8H3ClF3N
Molecular Weight	205.56 g/mol
Synonyms	4-Chloro-α,α,α-trifluoro-m-tolunitrile; 3-Trifluoromethyl-4-chlorobenzonitrile; 4-Chloro-3-trifluoromethylbenzonitrile; 2-Chloro-5-cyanobenzotrifluoride; 5-Chloro-2-(trifluoromethyl)benzonitrile; 4-Chloro-α,α,α-trifluoro-3-methylbenzonitrile; m-Tolunitrile, 4-chloro-α,α,α-trifluoro-
EINECS	217-080-2

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.