Description

4-(4-Fluorophenyl)Benzonitrile is a versatile aromatic nitrile derivative featuring a fluorinated biphenyl core structure. This compound serves as a critical high-purity building block and advanced pharmaceutical intermediate in modern synthetic chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its biphenyl scaffold for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes due to its stable, planar structure.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of high-performance engineering plastics and specialty polymers.
• Chemical Research & Development: Employed as a standard or reagent in methodological studies, including Suzuki-Miyaura and other cross-coupling reactions.
• Material Science: Investigated for use in the synthesis of metal-organic frameworks (MOFs) and other advanced functional materials.

Basic Information

Product Name	4-(4-Fluorophenyl)Benzonitrile
CAS No.	10540-31-5
Molecular Formula	C13H8FN
Molecular Weight	197.21 g/mol
Synonyms	4-Fluoro-4'-cyanobiphenyl; [1,1'-Biphenyl]-4-carbonitrile, 4'-fluoro-; p-Fluorophenylbenzonitrile; 4-Cyano-4'-fluorobiphenyl; 4-Fluorobiphenyl-4'-carbonitrile; 4'-Fluoro[1,1'-biphenyl]-4-carbonitrile; 4-(4-Fluorophenyl)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 4-(4-Fluorophenyl)Benzonitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	105 - 110 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.