Description

4-Fluoro-3-Nitrobenzonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a fluorine atom ortho to the nitrile, makes it a critical intermediate for constructing complex molecules with tailored electronic properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, where its structure influences charge transport and emission properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical characteristics.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial R&D labs.

Basic Information

Product Name	4-Fluoro-3-Nitrobenzonitrile
CAS No.	1009-35-4
Molecular Formula	C7H3FN2O2
Molecular Weight	166.11 g/mol
Synonyms	3-Nitro-4-fluorobenzonitrile; 4-Fluoro-3-nitrobenzenecarbonitrile; Benzonitrile, 4-fluoro-3-nitro-; 1-Fluoro-2-cyano-5-nitrobenzene; 2-Cyano-5-fluoro-1-nitrobenzene; 4-Fluoro-3-nitro-phenyl cyanide; 4-Fluoro-3-nitrobenzonitrile (technical grade)
EINECS	213-770-5

Quality Control

Our 4-Fluoro-3-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each lot, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.