Description

2,5-Dicyanobenzotrifluoride is a high-value, multi-functional aromatic intermediate featuring both cyano and trifluoromethyl substituents. This compound matters for its unique reactivity profile, enabling the synthesis of complex molecules with enhanced properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for constructing advanced heterocycles and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group imparts improved biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and high-performance materials with specific thermal or chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the electron-withdrawing nature of the substituents to tune metal center properties.
• Fluorescent Dye and Sensor Chemistry: Acts as a core structure in the synthesis of organic fluorophores and molecular sensors for analytical and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to biotechnology and advanced material sectors.

Basic Information

Product Name	2,5-Dicyanobenzotrifluoride
CAS No.	1483-44-9
Molecular Formula	C9H3F3N2
Molecular Weight	196.13 g/mol
Synonyms	2,5-Bis(cyano)-1-(trifluoromethyl)benzene; 1,4-Dicyano-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)-1,4-benzenedicarbonitrile; 2,5-Dicyanobenzotrifluoride; α,α,α-Trifluoro-2,5-dicyanotoluene; 2,5-Dicyano-α,α,α-trifluorotoluene; Benzene, 1,4-dicyano-2-(trifluoromethyl)-; 2,5-Dicyanobenzyl trifluoride
EINECS	Contact for details

Quality Control

Our 2,5-Dicyanobenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.