Description

3-Fluoro-5-Hydroxybenzonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a hydroxy and a fluoro substituent on the benzonitrile core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a monomer or functionalization agent for introducing polar cyano and hydroxy groups into polymer backbones to alter material properties.
• Chemical Research & Development: A valuable reagent for exploring new fluorination reactions, cross-coupling methodologies, and heterocycle formation in academic and industrial R&D settings.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments that require specific electronic and solubility characteristics.

Basic Information

Item	Details
Product Name	3-Fluoro-5-Hydroxybenzonitrile
CAS No.	473923-95-4
Molecular Formula	C7H4FNO
Molecular Weight	137.11 g/mol
Synonyms	5-Cyano-3-fluorophenol; 3-Fluoro-5-hydroxybenzenecarbonitrile; 3-Fluor-5-hydroxybenzolnitril (German); 3-Fluoro-5-hydroxy-benzonitrile; 3-Fluoro-5-cyanophenol; 3-Fluoro-5-phenol carbonitrile; Benzonitrile, 3-fluoro-5-hydroxy-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Hydroxybenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.