Description

2,5,6-Tri-o-Butyryl-Myo-Inositol-1,3,4-Trisphosphate-Hexakis(Acetoxymethyl) Ester is a sophisticated, cell-permeable derivative of inositol trisphosphate (IP3), designed for advanced biochemical research. This compound is critically important as a research-grade tool for studying intracellular calcium signaling pathways with high precision. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on signal transduction, neurobiology, and drug discovery.

Application

• Intracellular Calcium Signaling Research: Acts as a membrane-permeable precursor to IP3, used to induce and study calcium release from endoplasmic reticulum stores in live cells.
• Cell Biology & Physiology Studies: A key reagent for investigating the role of IP3 in processes like muscle contraction, neurotransmitter release, and cell proliferation.
• Drug Discovery & Screening: Utilized in high-throughput assays to identify and validate novel therapeutics targeting GPCR (G-protein-coupled receptor) pathways and calcium-dependent enzymes.
• Neuroscience Research: Employed to elucidate mechanisms of neuronal communication, synaptic plasticity, and the pathophysiology of neurological disorders.
• Biochemical Tool Development: Serves as a critical component in developing new probes and assays for real-time monitoring of second messenger dynamics.

Basic Information

Item	Detail
Product Name	2,5,6-Tri-o-Butyryl-Myo-Inositol-1,3,4-Trisphosphate-Hexakis(Acetoxymethyl) Ester
CAS No.	205247-51-4
Molecular Formula	C41H59O24P3
Molecular Weight	1028.81 g/mol
Synonyms	IP3 Hexakis(acetoxymethyl) Ester, Butyryl Derivative; myo-Inositol 1,3,4-trisphosphate, 2,5,6-tri-O-butyryl-, hexakis(acetoxymethyl) ester; 2,5,6-Tri-O-butyryl-myo-inositol 1,3,4-trisphosphate hexakis(acetoxymethyl) ester; caged IP3 analog; membrane-permeable IP3 ester; Ins(1,3,4)P3 / AM ester; Cell-permeable IP3 precursor
EINECS	Contact for details

Quality Control

Our 2,5,6-Tri-o-Butyryl-Myo-Inositol-1,3,4-Trisphosphate-Hexakis(Acetoxymethyl) Ester is manufactured under strict quality systems suitable for research applications. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This compound is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.