Description

[Pthr3]-Cdk5 Substrate CAS NO 1670273-47-8 is a specialized, high-purity peptide substrate designed for the specific and sensitive study of Cdk5 (Cyclin-dependent kinase 5) activity. This compound is critical for researchers and developers in the life sciences sector who require reliable and consistent biochemical tools. It is primarily utilized in kinase assay development, drug discovery screening, and fundamental research into neurological disorders and cell cycle regulation.

Application

• Kinase Activity Assays: Primary substrate for measuring Cdk5 enzymatic activity in in vitro biochemical assays.
• High-Throughput Screening (HTS): Used in automated platforms to identify and characterize potential Cdk5 inhibitors for therapeutic development.
• Biochemical Research: Fundamental tool for studying Cdk5 signaling pathways, substrate specificity, and phosphorylation kinetics.
• Diagnostic Development: Potential component in the development of assays for monitoring Cdk5-related pathological conditions.
• Pharmaceutical R&D: Essential for validating drug candidates targeting Cdk5 in cancer and neurodegenerative disease research.
• Academic Research: Supports investigations into neuronal development, synaptic function, and tau protein phosphorylation.

Basic Information

Product Name	[Pthr3]-Cdk5 Substrate
CAS No.	1670273-47-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cdk5 Substrate Peptide; Phosphoacceptor Substrate for Cdk5; Cdk5-specific Peptide Substrate; Cyclin-dependent kinase 5 Substrate; [P-Thr-3] Peptide; Kinase Substrate 1670273-47-8; Research Peptide for Cdk5 Assays
EINECS	Contact for details

Quality Control

Our [Pthr3]-Cdk5 Substrate is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and performance in standard kinase assays are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffers or DMSO
Biological Activity	Suitable for use in standard Cdk5 kinase assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.