Description

3-Cyano-2-Methoxybenzotrifluoride, 2-Cyano-6-(Trifluoromethyl)Anisole, 3-(Trifluoromethyl)-o-Anisonitrile is a high-value trifluoromethylated aromatic nitrile building block, distinguished by its unique combination of electron-withdrawing groups. This compound is essential for introducing the trifluoromethyl and cyano motifs into complex molecular architectures, significantly influencing the physicochemical and biological properties of target molecules. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of drugs targeting the central nervous system, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials requiring specific electronic properties.
• Organic Synthesis Reagent: A versatile reagent in cross-coupling reactions, nucleophilic aromatic substitution, and cyano group transformations for constructing complex heterocycles.
• Chemical Research & Development: Fundamental scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.

Basic Information

Product Name	3-Cyano-2-Methoxybenzotrifluoride
CAS No.	1017778-62-9
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	2-Cyano-6-(Trifluoromethyl)Anisole; 3-(Trifluoromethyl)-o-Anisonitrile; 2-Methoxy-α,α,α-trifluoro-m-tolunitrile; 3-Cyano-2-methoxybenzotrifluoride; 2-Methoxy-3-(trifluoromethyl)benzonitrile; 3-(Trifluoromethyl)-2-methoxybenzonitrile; 2-Methoxy-α,α,α-trifluoro-3-cyanotoluene; Benzonitrile, 2-methoxy-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Cyano-2-Methoxybenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.