Description

Fluorescent Dotap is a specialized cationic lipid derivative, chemically modified with a fluorescent tag for advanced detection and tracking applications. This compound is essential for researchers and developers requiring precise visualization of lipid-based delivery systems in real-time. It is primarily utilized in the life sciences sector for the formulation and study of fluorescently-labeled liposomes and lipid nanoparticles (LNPs), enabling critical insights into cellular uptake, biodistribution, and transfection efficiency.

Application

• Fluorescent Labeling of Liposomes & Lipid Nanoparticles (LNPs): Enables real-time tracking of drug delivery carriers in vitro and in vivo.
• Cellular Transfection & Uptake Studies: Visualizes the intracellular delivery pathway of nucleic acids (mRNA, siRNA, DNA).
• Biodistribution and Pharmacokinetic Research: Serves as a tracer to study the fate of lipid-based formulations in biological systems.
• Development of Diagnostic Imaging Probes: Used in the creation of contrast agents for fluorescence microscopy and imaging techniques.
• Membrane Biology Research: Investigates lipid membrane dynamics, fusion, and interactions.
• Quality Control for Lipid Formulations: Acts as an internal standard or marker to assess batch homogeneity and stability.

Basic Information

Product Name	Fluorescent Dotap
CAS No.	1010076-97-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,2-Dioleoyl-3-trimethylammonium-propane, Fluorescent conjugate; DOTAP, fluorescent derivative; N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium, fluorescent tag; Fluorescently-labeled cationic lipid; Fluoro-DOTAP; TMA-DOTAP, fluorescent; Lipofectamine analogue, fluorescent
EINECS	Contact for details

Quality Control

Our Fluorescent Dotap is produced under stringent quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to meet the exacting standards required for life science research. A detailed Certificate of Analysis (COA) documenting purity, fluorescence properties, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC/UV-Vis)	Conforms
Purity (HPLC)	≥ 95%
Fluorescence Emission Max	Contact for details
Solubility	Chloroform, Methanol, DMSO
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.