Description

Pamam Dendrimer Generation is a highly branched, monodisperse synthetic polymer with a well-defined, tree-like architecture. This precise structure is critical for applications requiring controlled size, surface functionality, and internal void spaces. It is an essential advanced material for researchers and developers in nanotechnology, pharmaceuticals, and diagnostics. The compound is identified by CAS No. 192948-77-9.

Application

• Drug Delivery Systems: As a nanocarrier for targeted and controlled release of therapeutic agents, enhancing drug solubility and bioavailability.
• Gene Transfection: Serving as a non-viral vector for the delivery of DNA, siRNA, or other genetic material into cells.
• Diagnostic Imaging: Functionalization with contrast agents (e.g., Gd(III) complexes for MRI) for use as highly efficient imaging probes.
• Catalyst Support: Providing a high-surface-area, functional scaffold for immobilizing metal nanoparticles or catalytic sites.
• Sensor Technology: Acting as a platform for chemical or biological sensors due to its modifiable surface groups and encapsulation properties.
• Surface Modification: Creating functional coatings with specific chemical properties for materials science and electronics applications.
• Cosmetic Formulations: Utilized in advanced skincare for enhanced encapsulation and delivery of active ingredients.

Basic Information

Product Name	Pamam Dendrimer Generation
CAS No.	192948-77-9
Molecular Formula	C22H48N10O4
Molecular Weight	516.7 g/mol
Synonyms	PAMAM Dendrimer, Generation 0, NH2 Terminal; Poly(amidoamine) Dendrimer, Generation 0; Starburst Dendrimer, G0-NH2; PAMAM G0; Ethylenediamine Core, Generation 0; Dendrimer, PAMAM, 0 Generation; 2,2',2'',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic Acid (common core derivative); Astramol
EINECS	Contact for details

Quality Control

Our Pamam Dendrimer Generation is produced under strict quality management protocols. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GPC to ensure monodispersity, purity, and consistent molecular weight. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Allow the container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Molecular Weight (GPC/SEC)	500 - 550 g/mol
Polydispersity Index (PDI)	≤ 1.05
Primary Amine Groups	4 groups per molecule (theoretical)
Solubility	Soluble in water, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.