Description

Kinase (Phosphorylating), Protein, Akt is a highly specific and active enzyme crucial for signal transduction research. This product, also known as Protein Kinase B (PKB), is essential for studying cellular processes like metabolism, proliferation, and survival. It is primarily used by researchers and developers in the pharmaceutical, biotechnology, and academic research sectors for drug discovery, biochemical assay development, and fundamental cell biology studies.

Application

• Biochemical Research & Assay Development: Used as a key reagent in in vitro kinase activity assays to study phosphorylation mechanisms and screen potential inhibitors.
• Drug Discovery & Target Validation: Serves as a critical target protein for developing and testing novel therapeutics for cancer, diabetes, and neurological disorders.
• Cell Signaling Pathway Analysis: Employed to investigate the PI3K/Akt/mTOR pathway, a central regulator of cell growth and survival.
• Diagnostic Kit Manufacturing: Utilized as a component in ELISA kits and other diagnostic tools for detecting phospho-Akt levels in clinical and research samples.
• Academic & Institutional Research: Supports fundamental studies in molecular biology, oncology, and metabolic disease research.
• Biopharmaceutical Production Support: Used in quality control and process development for biologics where Akt signaling is relevant.

Basic Information

Product Name	Kinase (Phosphorylating), Protein, Akt
CAS No.	148640-14-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Protein Kinase B (PKB); RAC-PK-alpha; Akt1; c-Akt; PKB Alpha; RAC Alpha Serine/Threonine-Protein Kinase; Proto-oncogene c-Akt; v-akt Murine Thymoma Viral Oncogene Homolog 1
EINECS	Contact for details

Quality Control

Our Kinase (Phosphorylating), Protein, Akt is produced and tested under stringent conditions to ensure high purity, specific activity, and batch-to-batch consistency, suitable for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, activity, and stability data. We adhere to rigorous quality management principles to support our global clients in pharmaceutical R&D and advanced life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Aliquot upon receipt to avoid repeated freeze-thaw cycles and minimize moisture uptake. Handle with appropriate laboratory precautions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solution
Identification (Activity)	Conforms (Specific kinase activity confirmed)
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ XX units/mg protein (Contact for lot-specific data)
Endotoxin Level	< 1.0 EU/μg (for cell culture grades)
Protein Concentration	Determined by Bradford or similar method
Buffer Composition	Tris-HCl, Glycerol, DTT, etc. (Grade specific)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.