Description

n-Hexanoyl-L-Homoserine Lactone (C6-HSL) is a high-purity, synthetic N-acyl homoserine lactone (AHL) quorum sensing signaling molecule. This compound is essential for researchers and industries studying and manipulating bacterial communication pathways, particularly in Gram-negative bacteria. It is a critical reagent for applications in microbiology, anti-biofilm research, and the development of quorum sensing inhibitors.

Application

• Microbiological Research: Used as a standard agonist to study and manipulate quorum sensing (QS) systems in bacteria such as Pseudomonas aeruginosa, Vibrio species, and other AHL-responsive organisms.
• Anti-Virulence & Anti-Biofilm Studies: A key tool for screening and developing novel anti-infective agents that disrupt bacterial communication without causing growth inhibition, thereby reducing selective pressure for resistance.
• Synthetic Biology: Employed as an inducer or signaling molecule in engineered genetic circuits and biosensors designed to detect or respond to specific bacterial populations.
• Agricultural Research: Investigated for modulating plant-microbe interactions, potentially influencing plant defense mechanisms or the efficacy of biocontrol agents.
• Industrial Biotechnology: Can be used to synchronize population-wide behaviors in fermentation processes or to control the production of specific metabolites in engineered bacterial systems.

Basic Information

Product Name	n-Hexanoyl-L-Homoserine Lactone
CAS No.	147852-83-3
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	N-Hexanoyl-L-homoserine lactone; C6-HSL; N-(3-Oxooctanoyl)-L-homoserine lactone; N-Caproyl-L-homoserine lactone; Hexanoyl homoserine lactone; AHL (C6); Quorum Sensing Molecule C6; N-3-Oxooctanoylhomoserine lactone; N-(3-Oxooctanoyl)homoserine lactone
EINECS	Contact for details

Quality Control

Our n-Hexanoyl-L-Homoserine Lactone is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to guarantee product integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.