Description

4-Fluoroisophthalonitrile is a high-purity fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and nitrile functional groups, makes it a versatile precursor for creating complex heterocyclic systems and functional materials. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors, as well as by material scientists working on specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a core building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer & Resin Modifier: Incorporated into high-performance polymers to improve thermal stability, chemical resistance, and dielectric properties.
• Organic Light-Emitting Diodes (OLEDs): Utilized in the synthesis of electron-transport materials and host materials for OLED devices.
• Coordination Chemistry & Ligand Design: The nitrile groups act as ligands for metal complexes used in catalysis and material science.

Basic Information

Product Name	4-Fluoroisophthalonitrile
CAS No.	13519-90-9
Molecular Formula	C8H3FN2
Molecular Weight	146.12 g/mol
Synonyms	1,3-Dicyano-5-fluorobenzene; 5-Fluoroisophthalonitrile; 4-Fluorobenzene-1,3-dicarbonitrile; Isophthalonitrile, 4-fluoro-; 5-Fluoro-1,3-benzenedicarbonitrile; 4-Fluorobenzene-1,3-dinitrile; 13519-90-9; AI3-26052
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoroisophthalonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	165 - 170 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.