Description

5,12-Naphthacenedione, 10-3-(3-cyano-4-morpholinyl)-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy- is a complex, high-value synthetic intermediate with a unique molecular architecture. This compound is critical for advanced research and development in pharmaceutical chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for its role as a key building block in complex molecule construction.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel anthracycline analogs and other complex bioactive molecules.
• Anticancer Drug Research: Used in the research and development of potential chemotherapeutic agents due to its naphthacenedione core, a structure class known for intercalating with DNA.
• Biochemical Research: Employed as a standard or reference compound in studies investigating structure-activity relationships (SAR) and mechanism of action.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing production processes for target active pharmaceutical ingredients (APIs).
• Academic Research: A valuable compound for universities and research institutes exploring new organic synthetic methodologies and carbohydrate chemistry.

Basic Information

Product Name	5,12-Naphthacenedione, 10-3-(3-cyano-4-morpholinyl)-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-
CAS No.	88254-07-3
Molecular Formula	C32H33N3O13
Molecular Weight	667.62 g/mol
Synonyms	10-[(2,6-Dideoxy-3-C-cyano-4-O-methyl-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 3'-Cyano-3'-deamino-4-O-methyl-4-demethoxydaunorubicin; 4-O-Methyl-3'-cyano-3'-deamino-4-demethoxydaunorubicin; 3'-Cyano-4-O-methylcarminomycin; Idarubicin related compound; 3'-Cyano-4-O-methyl-11-deoxycarminomycinone glycoside; 4-O-Methyl-3'-cyanodaunorubicin analog.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for research and pharmaceutical development. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing key parameters such as assay by HPLC, related substances, and residual solvents. We support compliance with cGMP principles where required for non-clinical and clinical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single impurity ≤ 2.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.