Description

Carzinophilin is a potent, naturally occurring antitumor antibiotic compound, also known as Carzinocidin, derived from *Streptomyces* species. This bioactive agent is of significant interest in pharmaceutical research and development due to its unique mechanism of action, which involves DNA alkylation and cross-linking, leading to the inhibition of cancer cell proliferation. It serves as a critical reference standard and active pharmaceutical ingredient (API) for researchers and manufacturers in the oncology and life sciences sectors, particularly for studying novel chemotherapeutic agents and developing targeted cancer therapies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the discovery and development of novel anticancer drugs.
• Oncology Studies: Used in biochemical and cellular assays to investigate mechanisms of DNA damage, apoptosis, and cell cycle arrest in cancer models.
• Academic & Clinical Research: Employed as a tool compound in universities and research institutes for studying tumor biology and evaluating the efficacy of combination therapies.
• Biochemical Reagent: Functions as a precise biochemical reagent for enzymatic studies and target validation in molecular pharmacology.
• Quality Control & Standardization: Essential for analytical method development, validation, and quality control testing of related pharmaceutical products in GMP environments.

Basic Information

Product Name	Carzinophilin
CAS No.	1403-28-7
Molecular Formula	C15H18N4O8S2
Molecular Weight	446.45 g/mol
Synonyms	Carzinocidin; Carzinophilin A; NSC-525816; Antibiotic from Streptomyces sahachiroi; 5,12-Diethyl-5,10-dihydroxy-1,8-diazonia-4,9,13,16-tetraoxo-2,7,11,15-tetrathiahexadeca-3,14-diene-6,11-diylium-1,8-diolate
EINECS	Contact for details

Quality Control

Our Carzinophilin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support research and GMP-grade requirements with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Assayed; report provided with COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.