Description

Actinomycin S3 is a potent antibiotic compound belonging to the actinomycin family, known for its complex chromophore-peptide structure. Its primary value lies in its ability to intercalate into DNA, making it a critical agent for inhibiting transcription in biochemical research and a reference standard in analytical studies. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require high-purity biochemical tools for oncology research, molecular biology, and antibiotic mechanism studies.

Application

• Biochemical research as a potent inhibitor of DNA-dependent RNA synthesis.
• Reference standard in analytical chemistry for quality control of related antibiotic products.
• Tool compound in oncology and cancer research for studying transcription inhibition.
• Component in microbiological studies to investigate antibiotic mechanisms of action.
• Use in molecular biology laboratories for experimental protocols requiring transcription blockers.
• Potential use in the development and calibration of bioanalytical assays (e.g., HPLC, LC-MS).

Basic Information

Product Name	Actinomycin S3
CAS No.	11097-67-9
Molecular Formula	C62H86N12O16
Molecular Weight	1255.4 g/mol
Synonyms	Actinomycin S3; Actinomycin C3; Actinomycin IV; Sanamycin; Actinomycin D analogue; NSC 31083; Antibiotic from Streptomyces parvulus; 2-Amino-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxylic acid bis[(5S,8S,9S,10S)-5,9-diamino-10-(2-amino-2-oxoethyl)-8-(hydroxymethyl)-2,6-dioxo-1,3-diazaspiro[4.5]dec-7-yl] ester
EINECS	Contact for details

Quality Control

Our Actinomycin S3 is produced and tested under strict quality management systems to ensure the highest standards of purity and consistency for research applications. Each batch is analyzed using advanced techniques including HPLC and spectroscopic methods to confirm identity and potency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storing at 2-8°C is recommended. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.