Description

Actinomycin is a potent polypeptide antibiotic complex, primarily known for its ability to bind to DNA and inhibit transcription. This mechanism makes it a critical research tool in molecular biology and a cornerstone in the development of chemotherapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for studying transcription mechanisms and cancer research. The product Actinomycin CAS NO 1402-38-6 is supplied to meet the stringent demands of these advanced applications.

Application

• Pharmaceutical Research & Development: Used as a key biochemical tool to inhibit RNA synthesis in studies of gene expression and transcription.
• Oncology Research: Serves as a reference standard and active component in cancer research due to its historical and ongoing relevance in chemotherapy.
• Biochemical Assays: Employed in various in vitro assays to study DNA-protein interactions and transcriptional regulation.
• Antibiotic Studies: Acts as a model compound in microbiological research to understand the action of polypeptide antibiotics.
• Cell Biology: Utilized to synchronize cells in the G1 phase of the cell cycle for cell cycle analysis.
• Veterinary Medicine: Has applications in veterinary oncology for the treatment of certain tumors in animals.

Basic Information

Product Name	Actinomycin
CAS No.	1402-38-6
Molecular Formula	C62H86N12O16
Molecular Weight	1255.42 g/mol
Synonyms	Actinomycin D; Dactinomycin; Actinomycin C1; Meractinomycin; Actinomycin IV; Actinomycin AIV; NSC-3053; Cosmegen; Lyovac Cosmegen
EINECS	Contact for details

Quality Control

Every batch of Actinomycin is subjected to rigorous analytical testing to ensure identity, purity, and potency. Our quality assurance protocols are designed to meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA), detailing specifications and test results, is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is strictly light-sensitive and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and maintenance under inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	Red crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.