Description

Chartreusin, Sodium Salt is a chemically modified derivative of the natural antibiotic chartreusin, designed for enhanced solubility and stability in aqueous formulations. This compound is valued for its potent biological activity, making it a critical intermediate and research tool in advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in the fields of oncology and infectious disease.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in preclinical studies for novel anti-cancer and antimicrobial agents.
• Antibiotic Mechanism Studies: Used in biochemical and microbiological research to investigate the mode of action of chartreusin-class antibiotics against DNA.
• Chemical Synthesis: Acts as a versatile sodium salt precursor for further chemical modifications and the synthesis of novel chartreusin analogs with tailored properties.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of anthracycline-like compounds.
• Bioconjugation Studies: Utilized in the development of antibody-drug conjugates (ADCs) or other targeted drug delivery systems due to its potent cytotoxic activity.

Basic Information

Product Name	Chartreusin, Sodium Salt
CAS No.	1393-72-2
Molecular Formula	C34H31NO12•Na
Molecular Weight	~668.6 g/mol
Synonyms	Chartreusin sodium; NSC 5159; Sodium Chartreusinate; Chartreusin Na salt; Antibiotic X-465A sodium salt; Chartreusin (sodium form); 4,6-Dideoxy-4-[[(2,6-dideoxy-4-O-β-D-glucopyranosyl-α-L-lyxo-hexopyranosyl)oxy]amino]-α-L-lyxo-hexopyranosyl]oxy]-1,2,3,4,6,11-hexahydro-3,5,7,10,12-pentahydroxy-6,11-dioxo-2-naphthacenecarboxylic acid sodium salt
EINECS	Contact for details

Quality Control

Our Chartreusin, Sodium Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research-grade materials. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange-brown powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 1.0%
Biological Activity	Assayed; report with COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.