Description

Mitomycin D is a potent antibiotic and antitumor agent belonging to the mitomycin family of natural products. This compound is of significant interest in biochemical and pharmaceutical research due to its ability to cross-link DNA, inhibiting cellular replication. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the life sciences sector. Key applications include oncology research, molecular biology studies, and the development of novel chemotherapeutic agents.

Application

• Oncology Research: Used as a reference standard in studies investigating DNA alkylation, cross-linking mechanisms, and the development of new anticancer therapies.
• Biochemical Reagent: Employed in laboratory settings to study cell cycle arrest, apoptosis, and the effects of DNA damage on cellular processes.
• Pharmaceutical Development: Serves as a key intermediate or building block in the synthesis and quality control of more complex antitumor compounds.
• Microbiology Studies: Acts as a potent antibiotic in research focused on bacterial inhibition and mechanism of action studies.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in chemical biology and medicinal chemistry.

Basic Information

Product Name	Mitomycin D
CAS No.	10169-34-3
Molecular Formula	C16H21N3O6
Molecular Weight	351.36 g/mol
Synonyms	7-Aminomitomycin; Mitomycin D; Antibiotic FR 900482; FR-900482; 6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione carbamate (ester); Mitomycin derivative
EINECS	Contact for details

Quality Control

Our Mitomycin D is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with relevant guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider keeping the material in a freezer at -20°C under desiccant. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.