Description

Actinomycin K is a potent polypeptide antibiotic belonging to the actinomycin family, known for its characteristic chromophore structure. This compound is primarily valued for its ability to intercalate into DNA, inhibiting transcription, which makes it a critical agent in biochemical and pharmacological research. It is essential for researchers and manufacturers in the life sciences sector, particularly those developing anticancer therapeutics and studying molecular genetics.

Application

• Anticancer Research: Used as a model compound in studies investigating DNA intercalation and the inhibition of RNA synthesis.
• Biochemical Tool: Employed in molecular biology laboratories to study transcription mechanisms and gene expression.
• Pharmaceutical Development: Serves as a reference standard and a lead compound in the discovery and development of novel chemotherapeutic agents.
• Microbiological Studies: Applied in research to understand its antibiotic properties against various Gram-positive bacteria.
• Cell Biology: Utilized in experiments to induce apoptosis and study cell cycle arrest in cultured cell lines.

Basic Information

Product Name	Actinomycin K
CAS No.	11011-00-0
Molecular Formula	C62H86N12O16
Molecular Weight	1255.42 g/mol
Synonyms	Actinomycin C3; Actinomycin K; Actinomycin VII; Antibiotic K; Dactinomycin K; Actinomycin C3; Actinomycin K1; NSC 62776
EINECS	Contact for details

Quality Control

Our Actinomycin K is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analysis, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is kept sealed in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Red crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.