Description

Mitomycin C is a potent antineoplastic antibiotic derived from *Streptomyces caespitosus*. This compound is a critical alkylating agent that cross-links DNA, making it a cornerstone in specific chemotherapeutic regimens. It is essential for pharmaceutical manufacturers, research institutions, and laboratories focused on oncology drug development and advanced biochemical studies. Mitomycin C CAS NO 50-07-7 is supplied under stringent quality controls to ensure reliability for sensitive applications.

Application

• Oncological Chemotherapy: A key component in the treatment of various cancers, including gastric, pancreatic, and bladder carcinomas, often used in combination therapies.
• Pharmaceutical Manufacturing: Serves as the active pharmaceutical ingredient (API) in injectable formulations for clinical use.
• Biomedical Research: Utilized as a DNA cross-linking agent in molecular biology and genetics research to study DNA repair mechanisms and cell cycle arrest.
• Ophthalmic Surgery: Applied as an adjunct in procedures like trabeculectomy to modulate wound healing and prevent scarring.
• Antibiotic Research: Studied for its potent antibacterial properties derived from its natural source.
• Biochemical Tool Compound: Used in vitro to induce senescence or apoptosis in cell culture studies.

Basic Information

Product Name	Mitomycin C
CAS No.	50-07-7
Molecular Formula	C15H18N4O5
Molecular Weight	334.33 g/mol
Synonyms	Mitomycin; Mitomycin-C; Ametycine; Mutamycin; 7-Amino-9α-methoxymitosane; NSC 26980; MIT-C; Antibiotic MA 1447
EINECS	200-008-6

Quality Control

Our Mitomycin C is produced and tested to meet exacting standards suitable for pharmaceutical and research applications. Each batch undergoes comprehensive analysis, including identity confirmation, purity assay, and impurity profiling via advanced chromatographic methods. A Certificate of Analysis (COA) detailing all test results is provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or under refrigeration (2-8°C) as specified. Due to its sensitivity to light and tendency for oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain stability and potency. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Blue-violet to dark blue crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.