Description

5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)- is a complex, high-purity chemical compound primarily known for its role as a key intermediate in advanced pharmaceutical synthesis. This compound, identified by CAS No. 75363-85-8, is critical for research and development in the life sciences sector due to its specific stereochemistry and functional groups. It is essential for manufacturers and research institutions focused on developing novel therapeutic agents, particularly in the fields of oncology and antibiotics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly anthracycline-class compounds.
• Oncology Research: Used in the research and development of novel chemotherapeutic agents targeting specific cancer pathways.
• Antibiotic Development: Acts as a precursor in the synthesis of advanced antibiotic molecules for combating resistant bacterial strains.
• Biochemical Research: Employed as a standard or reagent in biochemical assays and studies involving DNA intercalation or topoisomerase inhibition.
• Process Development: Utilized by process chemists for scaling up and optimizing synthetic routes for complex molecules in a GMP environment.
• Academic Research: A valuable compound for universities and research institutes conducting studies in medicinal chemistry and organic synthesis.

Basic Information

Product Name	5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-
CAS No.	75363-85-8
Molecular Formula	C26H30ClNO11
Molecular Weight	567.97 g/mol
Synonyms	Daunorubicin Hydrochloride; Daunomycin Hydrochloride; (8S-cis)-Daunorubicin Hydrochloride; Cerubidine Hydrochloride; Rubidomycin Hydrochloride; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride; Daunorubicin HCl; RP-13057 Hydrochloride.
EINECS	Contact for details

Quality Control

Our Daunorubicin Hydrochloride is manufactured under strict quality control protocols to ensure it meets the stringent requirements for pharmaceutical intermediates. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, utilizing advanced analytical techniques such as HPLC and NMR. Certificates of Analysis (COA) are provided with every shipment, detailing all test results. We can support development with material suitable for research, pre-clinical, and cGMP manufacturing phases, ensuring supply chain reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Orange-red to red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.