Description

9,11-Dioxa-2-aza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-, 9H-fluoren-9-ylmethyl ester (9CI) is a sophisticated, high-purity chemical building block designed for advanced research and synthesis. This compound is of significant value in the development of novel materials and active pharmaceutical ingredients (APIs), particularly in oligonucleotide and prodrug chemistry. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, biotechnology, and specialty chemical industries for creating next-generation therapeutics and high-value fine chemicals.

Application

• Phosphoramidite Monomer for Oligonucleotide Synthesis: A critical building block in the solid-phase synthesis of antisense oligonucleotides, siRNA, and other therapeutic nucleic acids.
• Advanced Prodrug Development: Used in the design and synthesis of prodrugs, where its unique structure can be utilized to improve drug solubility, stability, and targeted delivery.
• Specialty Polymer Chemistry: Serves as a key monomer or modifier in the synthesis of functional polymers with specific biological or material properties.
• Chemical Biology Research: Employed as a tool compound or linker in bioconjugation strategies and the study of biological pathways.
• Pharmaceutical Intermediate: An essential high-purity intermediate in multi-step synthetic routes for complex active pharmaceutical ingredients (APIs).
• Material Science Research: Investigated for creating novel organic materials with potential applications in electronics or sensing.

Basic Information

Item	Details
Product Name	9,11-Dioxa-2-aza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-, 9H-fluoren-9-ylmethyl ester (9CI)
CAS No.	147190-40-7
Molecular Formula	C53H55N2O8P
Molecular Weight	879.00 g/mol
Synonyms	Fmoc-protected Cyanoethyl Phosphoramidite; DMT-protected Phosphoramidite Monomer; N-Diisopropyl Cyanoethyl Phosphoramidite; 2-Cyanoethyl N,N-diisopropylphosphoramidite derivative; Oligonucleotide Synthesis Reagent; Prodrug Synthesis Intermediate; 7-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-9,11-dioxa-2-aza-10-phosphatridecanoic acid 9H-fluoren-9-ylmethyl ester
EINECS	Contact for details

Quality Control

Our production of this high-value building block adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR (¹H and ³¹P), and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and suitability for oligonucleotide synthesis or pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will lead to decomposition. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
³¹P NMR Purity	Single major peak, conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.