Description

1,N6-Ethenoadenine is a modified nucleobase derivative, specifically an etheno-bridged adenine analog. This compound is a valuable biochemical tool and research chemical used in the study of nucleic acid structure, mutagenesis, and adduct formation. It serves as a critical intermediate and reference standard in analytical chemistry and life science research for laboratories and pharmaceutical development companies.

Application

• Biochemical Research: Used as a probe to study DNA/RNA damage, mutagenesis, and the biological effects of etheno adducts.
• Analytical Reference Standard: Serves as a high-purity standard for the quantification and identification of ethenoadenine adducts in biological samples via HPLC, LC-MS, or GC-MS.
• Pharmaceutical Development: Employed in the research and development of novel therapeutics targeting DNA repair pathways or studying carcinogenic processes.
• Toxicology Studies: Utilized as a model compound to investigate the metabolic pathways and toxicological impact of environmental alkylating agents.
• Academic Research: A key reagent for universities and research institutes focusing on chemical biology, structural biology, and genetic toxicology.

Basic Information

Product Name	1,N6-Ethenoadenine
CAS No.	13875-63-3
Molecular Formula	C7H7N5
Molecular Weight	161.16 g/mol
Synonyms	1,N6-Ethenoadenine; 1,N6-Etheno-2'-deoxyadenosine (related nucleoside); ε-Adenine; Ethenoadenine; 1,N6-Etheno-adenine; 3H-Imidazo[2,1-i]purine; Adenine, 1,N6-etheno-
EINECS	Contact for details

Quality Control

Our 1,N6-Ethenoadenine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.