Description

Thymidine, [2-14C] is a carbon-14 radiolabeled nucleoside essential for advanced life science research. This compound is a critical tool for tracing and quantifying DNA synthesis, cellular proliferation, and metabolic pathways. It is primarily utilized by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors for drug discovery, toxicology studies, and molecular biology applications.

Application

• DNA Synthesis & Cell Proliferation Assays: Used as a tracer to measure the rate of DNA replication and cell growth in vitro and in vivo.
• Pharmacokinetics & ADME Studies: Tracks the absorption, distribution, metabolism, and excretion of novel nucleoside-based therapeutics.
• Oncology Research: Investigates the mechanisms of anti-cancer drugs that target DNA synthesis in tumor cells.
• Virology & Microbiology: Studies viral replication cycles and the development of antiviral agents.
• Biochemical Pathway Analysis: Elucidates metabolic pathways involving thymidine and its phosphorylated derivatives.
• Autoradiography & Imaging: Serves as a radioactive probe for precise localization in tissue sections and bio-distribution studies.

Basic Information

Product Name	Thymidine, [2-14C]
CAS No.	13010-45-2
Molecular Formula	C₁₀H₁₄N₂O₅ * (14C)
Molecular Weight	Contact for details
Synonyms	1-(2-Deoxy-β-D-ribofuranosyl)-5-methyl[2-14C]uracil; 2'-Deoxy[2-14C]thymidine; [2-14C]Thymidine; dT[2-14C]; 5-Methyl-2'-deoxy[2-14C]uridine; Radiolabeled Thymidine; Thymidine-2-14C; Thymidine (2-14C)
EINECS	Contact for details

Quality Control

Our radiolabeled compounds are produced and controlled under a strict quality management system. Each batch of Thymidine, [2-14C] is analyzed to ensure high radiochemical purity and specific activity as specified. Comprehensive Certificates of Analysis (COA) detailing purity, activity, and solvent composition are provided with every shipment to ensure reproducible and reliable research results.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C. This product is hygroscopic (moisture-sensitive) and should be handled under appropriate conditions to minimize exposure to atmospheric moisture. For long-term storage, keep the container in a dedicated freezer.

Specification

Item	Specification
Appearance	White to off-white solid or solution
Identification (HPLC, MS)	Conforms to reference standard
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Solvent (if supplied as solution)	Ethanol:Water (7:3) or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.