Description

Phleomycin D1 is a glycopeptide antibiotic belonging to the bleomycin family, known for its ability to induce DNA strand breaks. This compound is a critical research tool in molecular biology and biochemistry, primarily valued for its selective action. It is essential for scientists and professionals in pharmaceutical research, biotechnology, and academic laboratories who require high-purity biochemical reagents for genetic studies and mechanism-of-action investigations.

Application

• Molecular Biology Research: Used as a selective agent in genetic engineering and transformation experiments, particularly in yeast and bacterial systems.
• Biochemical Studies: Employed to study DNA damage and repair mechanisms due to its DNA-cleaving properties.
• Antibiotic Research: Serves as a reference standard and lead compound in the development of novel antimicrobial and antitumor agents.
• Cell Culture & Selection: Acts as a screening agent in cell culture media to select for genetically modified cells containing resistance markers.
• Enzyme Inhibition Studies: Utilized in research to investigate its interaction with specific enzymes and cellular targets.
• Pharmaceutical Development: Used in early-stage discovery for evaluating cytotoxicity and therapeutic potential against various cell lines.

Basic Information

Product Name	Phleomycin D1
CAS No.	11031-11-1
Molecular Formula	C₅₅H₈₄N₂₀O₂₁S₂
Molecular Weight	1481.51 g/mol
Synonyms	Phleomycin D1; Phleomycin D-1; NSC-113373; Antibiotic LA 7017; Bleomycin A; Zorbamycin; Bleomycin family antibiotic; Glycopeptide antibiotic LA-7017
EINECS	Contact for details

Quality Control

Our Phleomycin D1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency. We adhere to relevant standards for biochemical reagents to support the integrity of your scientific work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Potency (Microbiological)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.