Description

2,3-Dichlorobenzylmagnesium Chloride, 0.25M In 2-Methyltetrahydrofuran is a versatile organometallic reagent supplied as a standardized solution for synthetic chemistry. This compound is a critical building block for the efficient introduction of the 2,3-dichlorobenzyl moiety into target molecules via Grignard reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing complex molecules in active pharmaceutical ingredient (API) development and medicinal chemistry research.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides that incorporate the dichlorobenzyl functional group.
• Ligand and Catalyst Preparation: Serves as a precursor for specialized ligands and organometallic catalysts used in cross-coupling and other catalytic processes.
• Advanced Material Development: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers with tailored properties.
• Custom Chemical and Contract Synthesis: A fundamental tool for fine chemical manufacturers and CROs/CMOs performing bespoke synthesis for clients.
• Academic and Industrial R&D: Enables novel bond-forming reactions in exploratory chemistry for new compound libraries and process optimization.

Basic Information

Item	Details
Product Name	2,3-Dichlorobenzylmagnesium Chloride, 0.25M In 2-Methyltetrahydrofuran
CAS No.	946491-90-3
Molecular Formula	C7H5Cl2MgCl (Solution in 2-MeTHF)
Molecular Weight	Contact for details
Synonyms	2,3-Dichlorobenzylmagnesium Chloride; (2,3-Dichlorophenyl)methylmagnesium Chloride; 2,3-Dichlorobenzyl Grignard Reagent; Magnesium, chloro(2,3-dichlorobenzyl)-; 2,3-Dichlorobenzylmagnesium Chloride solution; Grignard Reagent from 2,3-Dichlorobenzyl Chloride
EINECS	Contact for details

Quality Control

Every batch of our 2,3-Dichlorobenzylmagnesium Chloride solution is manufactured and analyzed under stringent quality systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing concentration, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting development through to commercial-scale production.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. The solution is highly volatile and easily oxidized; ensure containers are kept tightly sealed and allowed to equilibrate to room temperature before opening to minimize moisture ingress and pressure changes. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration	0.25 M in 2-Methyltetrahydrofuran (2-MeTHF)
Assay (Titration)	0.23 - 0.27 M
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (of active Grignard species)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.