Description

3,5-Dichlorobenzylmagnesium Chloride is a highly reactive organomagnesium reagent, specifically a Grignard reagent, essential for introducing the 3,5-dichlorobenzyl group into complex molecular frameworks. Its primary value lies in enabling precise carbon-carbon bond formation, a critical step in the synthesis of advanced pharmaceutical intermediates and specialty agrochemicals. This compound is particularly sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex, halogenated aromatic structures.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating active pharmaceutical ingredients (APIs) with dichlorobenzyl motifs, particularly in central nervous system and anti-infective drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides where the 3,5-dichloro substitution pattern enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the production of novel polymers and liquid crystals with specific electronic or optical properties derived from the dichlorinated aromatic core.
• Fine Chemical Production: Integral for custom synthesis and contract manufacturing of complex, high-value organic molecules for research and industrial applications.

Basic Information

Product Name	3,5-Dichlorobenzylmagnesium Chloride
CAS No.	107549-25-7
Molecular Formula	C7H5Cl3Mg
Molecular Weight	211.37 g/mol
Synonyms	(3,5-Dichlorophenyl)methylmagnesium chloride; Magnesium, chloro(3,5-dichlorophenyl)methyl-; 3,5-Dichlorobenzylmagnesium chloride solution; Grignard reagent 3,5-dichlorobenzylmagnesium chloride; (3,5-Dichlorobenzyl)magnesium chloride; 1-(Chloromagnesio)methyl-3,5-dichlorobenzene
EINECS	Contact for details

Quality Control

Our 3,5-Dichlorobenzylmagnesium Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing concentration, purity, and impurity profile. We adhere to cGMP principles where applicable, and our quality system is designed to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this reagent must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. The storage area must be cool, dry, and well-ventilated, away from any sources of ignition, moisture, or incompatible materials.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.